User’s Voice_Tokyo Univ. of Agriculture and Technology
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Tokyo University of Agriculture and Technology
Graduate School of Engineering,
Department of Applied Chemistry
Professor Keiji Mori
Development of Molecular Transformation Methods Based on Spatial Molecular Behavior
Our laboratory focuses on developing organic synthetic reactions centered on “spatial molecular behavior,” such as the spatial migration of atomic groups and through-space interactions.
In conventional organic transformation, it is common practice to install highly reactive functional groups at or near the reaction site. While reliable, this approach often leads to predictable ideas. We believe that by enabling atoms to migrate across space from distant positions—triggering reactions at sites that appear inert—we can achieve unprecedented molecular transformations.
To date, we have successfully developed transformations involving the spatial migration of hydrogen atoms and aromatic rings. The compounds obtained through these reactions are not only difficult to synthesize using conventional techniques but also serve as vital building blocks for pharmaceuticals, agrochemicals, and functional materials. Our ultimate goal is to create novel substances with innovative properties and functions through molecular transformations rooted in entirely new molecular behaviors.
The primary reason I choose EYELA is reliability. Having used their equipment since my student days, I have always had the impression that they provide robust, high-quality instruments with minimal downtime. Naturally, when I was appointed to TUAT and began setting up my own laboratory, EYELA was my first choice for essential equipment like chillers.
Furthermore, their exceptional after-sales care is a significant advantage. I must admit—and I often reflect on this with a bit of guilt—that whenever a minor issue arises, my immediate reflex is to contact EYELA support without hesitation. Despite my “knee-jerk” calls, their sales and technical representatives visit the lab promptly to provide assistance, which I truly appreciate.
We use the Personal Organic Synthesis Station (ChemiStation) daily due to its high utility. The ability to individually set the temperature and stirring speed for each vessel is indispensable for our reaction development research, and it has been incredibly helpful. I am also highly satisfied with the performance of our rotary evaporators and low temperature circulators (chillers); having used them for many years, their consistent operation remains a cornerstone of our laboratory work.
