• Compact concentrators designed to meet various needs
• Use centrifugal force, vacuum and heat to evaporate solvents rapidly from multiple biological or analytical samples
• Outline and corrosion resistance
| Model | CVE-2100 | CVE-2200 | CVE-3000 | CVE-3110 | |
| Applications |
For the concentration using microtubes and test tubes | For the concentration and solvent removal of small samples such as DNA, RNA, drugs, and metabolites | For the concentration of aqueous samples, DNA, RNA, drugs, natural products, and metabolites, as well as low-temperature concentration of biochemical samples | For the concentration and solvent removal of combinatorial chemistry and organic synthesis samples | |
| Applicable vessels |
Microtubes (1.5mL), Test tubes (10 to 13mm OD) | Microtubes (1.5mL), Test tubes (10 to 18mm OD), Vials (50mL), Deepwell plate (96 well), Centrifuge tubes (15, 50mL) | |||
| Chemical resistance | Water | Recommended | Recommended | Recommended | Recommended |
| Alcohol | Recommended | Recommended | Recommended | Recommended | |
| Weak acid | Caution | Caution | Recommended | Recommended | |
| Strong acid | Not recommended | Not recommended | Caution *1 | Caution *1 | |
| Organic solvent | Caution *2 | Caution *2 | Recommended | Recommended | |
| Wetted part (Material) | Chamber (stainless steel), Rotor (aluminum + anodized aluminum), Cover (PVC) | Chamber and rotor (stainless steel + Teflon® coating), Cover (glass + PVC) | |||
*1: Hydrochloric acid cannot be used.
*2: Alcohol can be used.
• Characteristics
♦ CVE-2100
◊ By connecting to diaphragm vacuum pump and cold trap, samples in microtubes (up to 24 tubes) or test tubes (up to 16 tubes) can be concentrated and dried.
◊ Temperature can be set according to the sample within the range of room temperature +5 to 80°C. Digital setting and display for excellent operability.
◊ The rotor can be easily removed for easy cleaning of the chamber.
◊ The height is kept low so that the inside of the chamber can be seen even when placed on a laboratory bench.
♦ CVE-2200
◊ It has a built-in vacuum pump. This compact diaphragm pump achieves a high vacuum of approximately 40hPa and offers excellent corrosion resistance.
◊ For solvents that are difficult to evaporate using the built-in vacuum pump, the device is equipped with a connection nozzle and pump selector switch for an external vacuum pump.
◊ Temperature can be set according to the sample within the range of room temperature +5 to 80°C. Digital setting and display for excellent operability.
♦ CVE-3000
◊ The temperature can be adjusted from 4℃ by running cooling water through the built-in cooling coil. Even biochemical samples that are sensitive to heat can be concentrated at low temperatures.
◊ Rotors for 15 and 50mL centrifuge tubes, which are frequently used in biochemical experiments, are available.
◊ The equipment has a slow-up mechanism when starting rotation and a slow-down mechanism when stopping rotation, preventing damage to test tubes and vials caused by sudden rotation shock.
◊ The inside of the cover is made of glass, while the outside has a double structure of a resin plate to protect the glass. The parts that come into contact with gas are made of glass to prevent corrosion and deformation caused by organic solvents.
♦ CVE-3110
◊ The chamber is coated with a special Teflon® coating that is resistant to acids and organic solvents used in combinatorial chemistry such as TFA, DMF, and DMSO.
◊ A variety of rotors are available for deep-well plates and centrifuge tubes compatible with combinatorial chemistry.
◊ When starting operation, the vacuum pump starts once the rotation speed has reached the set value, and when stopping, the pump stops after the vacuum is released, and then the rotation stops, which is a safety control.
◊ The cover has a double structure with an inner glass panel and an outer resin panel to protect the glass. Since the gas-contacting parts are made of glass, there is no risk of corrosion from organic solvents, and deformation is prevented.
♦ Specifications
| Product name | Centrifugal evaporator | |||
| Model | CVE-2100 | CVE-2200 | CVE-3000 | CVE-3110 |
| Cat. No. | 260560 | 260570 | 252170 | 260580 |
| Concentration method | Vacuum concentration using centrifugal force | |||
| Rotation speed range | 1400/1700rpm (50/60Hz) Fixed | 100 to 2000rpm (50/60Hz) | ||
| Temperature control range | OFF・room temperature +5 to 80°C | 4 to 80˚C | OFF・room temperature +5 to 80°C | |
| Vacuum pump | Sold separately | Built-in (diaphragm pump) | Sold separately | |
| Ultimate vacuum | 13.3hPa (10mmHg) or less | Internal pump: 40hPa, External pump: 13.3hPa | 0.13hPa | |
| Temperature control | PID control | |||
| Temperature setting ・display | Digital setting・display | |||
| Rotation setting ・display | － | Speed control knob (stepless control with slow-start function) | ||
| Safety functions | Independent overheat protector, motor brake (activates when the cover is opened) | Fixed overheat protector, motor brake (activates when the cover is opened), automatic vacuum pump release upon operation stop or power failure. | ||
| Rotor | Sold separately (See “Options” below) | |||
| Heater | 140W | 140W + 25W | 100W | |
| Motor | Induction motor output 3W | Brushless DC motor output 50W | ||
| Vacuum seal | Sealless magnetic drive mechanism | |||
| Vacuum gauge | Bourdon tube (-100 to 0kPa) | |||
| Nitrogen purge port・sterilization filter | 6.5mm diameter・0.2μm pore size | 6 to 13.5mm diameter・0.2μm pore size | ||
| Vacuum release valve | Manual, slow release mechanism | |||
| Temperature sensor | Thermistor | |||
| Chamber inner dimensions | 160 ID x 105H (mm) |
260 ID x 180(effective)H (mm) |
||
| Chamber material | Stainless steel | Stainless steel, special Teflon® coating | ||
| Cover material | Transparent PVC | Transparent PVC + glass (double-layer structure) | ||
| Connection diameter | Exhaust: 8 to 10mm OD | Exhaust: 13mm OD | ||
| Cooling water connection diameter | － |
One-touch connector 10mm ID, One-touch hose nozzle 10mm OD | － | |
| Connector material | PP | PPS | ||
| Connection tube material | － | Teflon® | － | |
| Ambient temperature range | 5 to 35˚C |
|||
| Power input | 1.5A, 150VA | 2.4A, 240VA | 3A, 300VA | 4A, 400VA |
| supply voltage | 220VAC 50/60Hz | 100VAC 50/60Hz | 220VAC 50/60Hz | 220VAC 50/60Hz |
| Outer dimensions (mm) | 240(250)W x 260(302)D x 230H | 240(254)W x 260(310)D x 260H | 368W x 348(412.5)D x 425H | 326W x 349(404)D x 397H (mm) |
| Weight | Approx. 8kg | Approx. 10kg | Approx. 29kg | Approx. 22kg |
◊ Performance values are at room temperature 20°C, rated power supply voltage, 50Hz, and no load.
◊ The temperature control range of CVE-3000 applies when using the built-in cooling water circulation coil (The low temperature circulator is sold separately).
◊ Dimensions in parentheses ( ) include protrusions.
• Data
♦ Evaporation data for CVE-2200
| Sample | Volume | Temperature | Time required |
| Acetone | 1mL x 16 pcs | 40℃ | 30min |
| Acetone | 1mL x 16 pcs | 60℃ | 24min |
| Acetone | 1mL x 16 pcs | 80℃ | 21min |
◊ Time required for complete evaporation of acetone.
◊ Condition: Room temperature: 25℃, Rotor R-2000C, Pump: Built-in
♦ Evaporation data for CVE-3100
| Sample | Volume | Temperature | Time required |
| TFA:methylene chloride (1:1) | 5mL x 48 pcs | 60℃ | 33min |
| DMF | 5mL x 48 pcs | 60℃ | 5hr 15min |
| Acetone | 5mL x 48 pcs | 80℃ | 31 min |
| Pure water | 5mL x 48 pcs | 80℃ | 4hr 25min |
◊ Time required for complete evaporation of each solution.
◊ Condition: Room temperature: 25℃, Rotor: R-3100C, Pump: GCD-136XN, Cold trap: UT-2000
• Options
♦ Rotors for CVE-2100・2200
| Product | Model | Cat. No. | Applicable vessels | Number of vessels |
 |
R-2000A | 188830 | Microtube 10.8mm OD (1.5mL) | 24 |
 |
R-2000B | 188840 | Test tube 10 to 13mm OD (Length 80 to 100mm) | 16 |
 |
R-2000C | 188850 | Test tube 10 to 13mm (Length 65 to 75mm) | 16 |
 |
R-2000D | 188860 | Test tube 10 to 13mm OD (Length 32 to 50mm) | 16 |
◊ A (Material: Stainless steel), B・ C・ D (Material: Aluminum, anodized)
♦ Rotors for CVE-3000・3110
| Product | Model | Cat. No. | Applicable vessels | Number of vessels |
 |
R-3100A | 192440 | Microtube (10.8mm OD, 1.5m) | 96 |
| － | R-3100B | 192450 | Test tube 10 to 12mm OD (Length 90 to 120mm) | 48 |
 |
R-3100C | 192460 | Test tube 16.5 to 18mm (Length 90 to120mm liquid-phase centrifuge tube) | 48 |
| － | R-3100D | 192470 | Test tube 17.5 to 18mm OD (Length 130 to 165mm) | 48 |
| － | R-3100E | 192480 | Vial 40.5 OD x 78.5mm, 50mL | 10 |
 |
R-3100F | 192490 | Swing rotor for deepwell plate (96 well) (86W x 128D x 44Hmm) | 2 |
 |
R-3100G | 192500 | Test tube ・Centrifuge tube (35 OD x 105mm) | 12 |
| － | R-3100H | 213010 | For CCX Test tube (24 OD x 150mm) | 12 |
| － | R-3100I | 252180 | 15mL Centrifuge tube (17 OD x 120mm) | 48 |
| － | R-3100J | 252190 | 50mL Centrifuge tube (29 OD x 115mm) | 18 |
| － | R-3100K | 253990 | Test tube 13 to 15mm OD (Length 90 to 150mm) | 48 |
◊ Material: Stainless steel, special Teflon® coating
• Related products
| Cold trap | UT-1000・UT-2000 |
| Diaphragm vacuum pump | EVP-1000・1100・1200
DTC・DTU series NVP series |