Column Flow Reactor MCR-1000

• Simple column flow reactor as an introductory model for continuous flow synthesis

MCR-1000

♦ With a simple setup comprising only a column and heating reactor, you can easily start flow synthesis using your existing liquid dispensing pump. This system is ideal as an introductory model for flow synthesis methods. MRC-1000 is equipped with refillable cartridge-style columns, it is also highly effective for catalyst screening applications.

♦ The aluminum block heating reactor, which enables highly accurate temperature control in the range of 50 to 200°C.

• Low-cost columns

♦ The columns are available in six sizes: 3, 5, and 10mm inner diameter x 50 and 100mm in length, and are made of either stainless steel or glass. Glass columns are effective for reactions that require acids.

♦ The columns consist of disposable stainless steel or glass tubes combined with column filters. This design reduces column costs to approximately one-tenth of conventional products. It also significantly reduces the effort required for column cleaning and catalyst replacement.

• Simple operation

♦ The toggle clamp mechanism is incorporated to secure the column to the heating reactor. Columns can be easily mounted by simply operating the lever (PAT).

♦ Two types of column connections are available: a simple one-liquid flow path and a gas-liquid dual-tube connection. Both liquid-liquid and gas-liquid reactions can be performed by replacing the one-liquid column end (included in the column set) with a gas-liquid column end (option).  The gas-liquid column end is ideal for gas-liquid catalytic reactions such as hydrogenation.

• Specifications

Product name	Column Flow Reactor (PAT.P)
Model	MCR-1000
Cat. No.	267950
Reaction method	Flow method（by liquid dispensing pump）
Reaction vessel	Stainless steel・glass tube (option)
Columns	3・5・10mm ID x 50・100mm length
Column mounting	By lever up/down (toggle clamp mechanism)
Max. pressure	Less than 1MPa
Temperature control range	50 to 200°C (aluminum block temperature)
Control accuracy	+1.0°C or less (aluminum block temperature)
Temperature control	Aluminum block jacket control, heating PID control
Temperature setting/display	Membrane keypad input・digital display
Sample inlet	One-liquid flow path/Gas-liquid dual tube connection (option)
Safety features	Temperature controller self-diagnostic function (variable upper temperature limit/sensor error), Independent overheat protector (thermal fuse), Earth leakage/Overcurrent breaker
Wetted part material	PTFE・PEEK・FFKM・SUS316・Glass
Connection tube・ Thread standards	1/16″ OD tube・No.10-32UNF
Ambient operating temperature	5 to 35℃
Power input	2.0A, 200VA
Supply voltage	100VAC  50/60Hz
Weight	Main unit: 2.9kg, Control unit:1.8kg
External dimensions(mm)	Main unit: 124W x 163D x 214H, Control unit: 80W x 220D x 151H

◊ The column set is sold separately.

• Options

• Column set

• Tube reactor MCR-PFR

This is a tube reactor for liquid phase reactions such as homogeneous catalysts. It is possible to wrap a PTFE tubing (sold separately) with 1/16 inch OD up to about 3m around the tube reactor and mount it to the MCR-1000 main unit.

• PTFE tubing 

• 0.5mm ID x 1/16″: Approx. 0.6mL
• 0.8mm ID x 1/16″: Approx. 1.5mL
• 1.0mm ID x 1/16″: Approx. 2.4mL

Note: These values are theoretical estimates based on a 3-meter tube length.

• Tubing

• Immobilized catalyst cartridges

This is a column tube filled with a catalyst for flow reactions with low pressure loss and high activity. It can be used by mounting it to the heating reactor immediately after opening. The column size is 5mm ID x 50mm in length, and the column material is glass. Three types of catalyst are available.

<Catalyst supply: Fujifilm Wako Pure Chemical Corporation>

◊ Storage conditions:  2 to 10°C

• SynpleFlow stand

The stand is equipped with a 4-built-in outlet (power capacity: 8A) for easy power management. The pull-out drawer on the front of the stand allows for convenient storage of column parts and small components. The column rack, attachable to either side of the stand, enables efficient and organized experimentation.

Model:  STT-1010
Cat. No. 276310

• SynpleFlow gas addition unit

This is a gas addition unit for hydrogenation reactions. It supplies hydrogen gas into the column at any flow rate. The wide operating differential pressure range allows for stable gas flow control even during pressure fluctuations. No need to adjust the gas source supply pressure each time.

It comes standard with the backflow prevention mechanism and the trap for reaction liquid, and prevents damage to the mass flow controller due to liquid contamination. In addition, for applications that do not use reaction liquid, you can also select a type without a backflow prevention trap (MFC-1100-H2). Equipped with 0 to 5VDC analog output terminal. By connecting to a data logger or recorder, it is possible to record and manage measured flow data during the reaction. Note that recorder output cable is sold separately.

Product Name:　SinpleFlow gas addition unit
Flow control range: 2 to 100mL/min
Maximum working pressure: less than 1.0MPa
Model: MFC-11GU
Cat. No.: 276320
◊ Please inquire about changing gas type and flow rate.

Product name: Recorder output cable for LCR and MCR
Cat. No.: 276280

Product name: Alarm input/output cable for LCR and MCR
Cat. No.: 276290

• Pressure regulating valve unit

The column internal pressure can be controlled at any desired value by operating the valve. The valve unit can be removed from the stand and installed anywhere you like, such as on an angle or a stand pole. It is equipped with a recorder output terminal, so measured values ​​can be output and recorded. Note that the output cord is sold separately.

Product Name:Pressure regulating valve A                                      Pressure adjustment range: 0 to 1.5MPa
Pressure value display: 0 to 3.5MPa, digital display
Model: BPR-1000A　
Cat. No.: 274450
Inlet: Right side

Product name: Pressure regulating valve B
Model: BPR-1000B
Cat. No.:No.274460
Inlet port: Left side

Product name: Torque, rotation, pressure signal output cord　
Cord length 2.5m
Model: ZO-2000
Cat. No.: 120890

• Medium and high pressure liquid dispensing pump 

EUI-22 features a linear-driven double-plunger mechanism, enabling stable liquid delivery with minimized pulsation.

Flow control range: 0.001 to 9.999mL/min
Discharge pressure: 20MPa (Model 110P), 35MPa (Model 110S)
Model: EUI-22-110P
Cat. No.: 278550
Wetted parts: PEEK

Model: EUI-22-110S
Cat. No.: 278560
Wetted part: Stainless steel